Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2017, Vol. 28 ›› Issue (1): 6 doi: 10.1007/s41365-016-0156-9

• NUCLEAR CHEMISTRY,RADIOCHEMISTRY,RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE • Previous Articles     Next Articles

Accuracy of left ventricular function from electrocardiography-gated myocardial perfusion SPECT by MyoMetrix in Chinese

Yang-Chun Chen 1, Ruo-Zhu Dai 2, Ke-Lian Zhang 2, Yong-Da Dong 2, Hui-Lin Zhuo 2, Qing-Mu Wang3   

  1. 1 Department of Nuclear Medicine, Quanzhou No.1 Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China
    2 Department of Cardiology, Quanzhou No.1 Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China
    3 Department of Ultrasound, Quanzhou No.1 Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China
  • Contact: Ruo-Zhu Dai E-mail:dairzcn@126.com
  • Supported by:

    This study was supported by the Natural Science Foundation of Fujian Province (No. 2015J01516).

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Yang-Chun Chen, Ruo-Zhu Dai, Ke-Lian Zhang, Yong-Da Dong, Hui-Lin Zhuo, Qing-Mu Wang. Accuracy of left ventricular function from electrocardiography-gated myocardial perfusion SPECT by MyoMetrix in Chinese.Nuclear Science and Techniques, 2017, 28(1): 6     doi: 10.1007/s41365-016-0156-9
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Abstract:

This work was to determine threshold values for accurate measurements of left ventricular end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) from electrocardiography-gated myocardial perfusion imaging (MPI) in Chinese, and these data were compared with those of echocardiography. A total of 110 patients with definite or suspected coronary artery disease were referred for both gated MPI and echocardiography within 1 week. The EDV, ESV, and EF automatically measured by MyoMetrix and echocardiography were analyzed using Bland–Altman plot correlation and paired t test. The results showed that these parameters quantified by MyoMetrix software were correlated, moderately to highly, with those on echocardiography (ρ, r ≥ 0.75, P < 0.01). However, the EF was not significantly correlated, with post-exercise MPI ESV of <15 mL or resting MPI ESV of <20 mL. At or above this ESV value, EF was underestimated by MyoMetrix (t ≥ 4.60, P < 0.01). In a word, a small ESV was underestimated by MyoMetrix, which could lead to EF overestimation. On the contrary, a normal or large ESV was overestimated by MyoMetrix, which led to EF underestimation.

Key words: Myocardial perfusion imaging, Left ventricular function, Software