Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2009, Vol. 20 ›› Issue (3): 152-156 doi: 10.13538/j.1001-8042/nst.20.152-156

• RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICIN • Previous Articles     Next Articles

A study on Fricke-PVA-xylenol orange hydrogel dosimeter for E-beam radiotherapy

CAO Fangqi1 YANG Liming1,* CHEN Jie1 LIN Han1 FAN Jinchen1 RONG Liang1 LUO Wenyun1 ZHA Yuanzi2 WU Guohua2   

  1. 1Department of Chemical Engineering and Technology, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China 2Department of Radiation Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
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CAO Fangqi, YANG Liming, CHEN Jie, LIN Han, FAN Jinchen. A study on Fricke-PVA-xylenol orange hydrogel dosimeter for E-beam radiotherapy.Nuclear Science and Techniques, 2009, 20(3): 152-156     doi: 10.13538/j.1001-8042/nst.20.152-156

Abstract:

A Fricke-PVA-xylenol orange (FPX) hydrogel dosimeter, in good transparency, was prepared by physical crosslinking for three-dimensional dose measurements. The process of mixing the chemical dosimeter with the PVA solution was carried out at room temperature, which reduced the influence of auto-oxidation rate. Gradation in color was obviously observed with different distance from the radiation source after 6 MeV electron beam irradiation for radiotherapy. The effects of irradiation dose and three components of the FPX gel dosimeter, i.e. ferrous ions, xylenol orange (XO) and sulphuric acid on sensitivity and stability of dose response were investigated by UV-vis spectrophotometric measurement. The dose response of the FPX gel dosimeter was linear in the range 0~2.0 Gy. The orthogonal test was employed to find the optimal composition of the gel dosimeter with a sensitivity of about 0.095 cm-1·Gy-1. It was found that XO concentration greatly affected the sensitivity of dose response and lower concentrations of the ferrous ion and XO gave higher sensitivity within the range 0~2.0 Gy.

Key words: Fricke-PVA-xylenol orange (FPX), Hydrogel dosimeter, Radiotherapy, Electron-beam