Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2018 Impact factor 0.961

Nuclear Science and Techniques ›› 2008, Vol. 19 ›› Issue (6): 370-375

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Ultrasonic-assisted synthesis and strepavidin conjugation of amino-magnetic nanoparticles

LIU Li1 JIAO Qinghua1 PENG Cheng2 HE Shijiang2 WANG Lihua2,*   

  1. 1 School of Materials Science and Engineering, Shanghai University, Shanghai 201800, China 2 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
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LIU Li, JIAO Qinghua, PENG Cheng, HE Shijiang, WANG Lihua. Ultrasonic-assisted synthesis and strepavidin conjugation of amino-magnetic nanoparticles.Nuclear Science and Techniques, 2008, 19(6): 370-375

Abstract: MNPs are widely used in biotechnology, magnetic resonance imaging, catalysis and other areas. In this paper, we propose a simple, quick, inexpensive and efficient way to prepare amino-MNPs with sonication-assisted process. The amino-MNPs prepared by hydrolyzing TEOS and APS were characterized by SEM, TEM and FTIR. Conjugation of SA and amino-MNPs was also studied. The biotin bound capacity of prepared SA coated amino-MNPs was 1.824 nmol/mg, which well meet the need of biological application.

Key words: Magnetic nanoparticles, Strepavidin, Biotin bound capacity, Sonication-assisted surface treatment