Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2002, Vol. 13 ›› Issue (2): 72

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Clinical analysis of bone scanning in solitary lesion

ZHU Jun, ZHU Rui-Sen, ZHU Ji-Fang   

  1. The 6th People's Hospital, Shanghat 200233
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ZHU Jun, ZHU Rui-Sen, ZHU Ji-Fang. Clinical analysis of bone scanning in solitary lesion.Nuclear Science and Techniques, 2002, 13(2): 72

Abstract: A rational analysis procedure for solitary lesions on whole bone scan ning was offered. This study was undertaken to analyze retrospectively solitary le sions which obtained final diagnose through the following aspects: (1) diagnosis of bone metastasis, (2) the incidence of bone metastasis in different tumor, (3) the most possible lesion sites indicating bone metastasis, (4) morphological analysis of solitary lesions. The results are: (1) The incidence of solitary lesions in 2465 cases on wholr bone scanning is 15.3%. (2) The rate of bone metastasis is 24.8% in 282 patients with primary malignancy. The rate of bone metastasis is 6.3% in 64 patients without primary malignancy, and the total diagnostic rate of bone metastasis is 21.4% in 346 patients. (3) In patients with primary malignancy, the incidence of bone metastasis of solitary lesions is as follows respectively: bronchi cancer 36.1%(22/61); breast cancer 23.8%(20/84); prostate gland 17.2%(5/29); other urinary system cancer 22.2%(4/18): G.L. system cancer 16.9%(10/59); others 29.0%(9/31). There is no significant ditference in different cancer. (4) In patients without primary malignancy, 93.7%(60/64) of solitary lesions are benign. (5) From anatomical point of view, we found the diagnostic rate of bone metastasis is as follow: 30% in spine; 34.2% in pelvis; 36.4% in skull: 10.8% in other bones. There are significant differences in four groups. It is concluded that: (1) The diagnostic rate of bone metastasis in solitary lesions is 21.4%. (2) The most possible solitary lesions indicating osseous tumor spread are at spine, pelvic and skull. (3) Special attention to "cold" and streak like lesions should be paid. (4) A clinical analysis procedure for diagnosis of solitary lesions has been summarized out here.

Key words: Bone neoplasm, Radionuclide imaging, Metastases