Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2018 Impact factor 0.961

Nuclear Science and Techniques ›› 1999, Vol. 10 ›› Issue (1): 28

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Application of pharmacokinetics local model to evaluate renal function

WAN Weixing, CAO Guoxian, YU Huixin   

  1. Jianyuan Hospital, State Key Laboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063
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WAN Weixing, CAO Guoxian, YU Huixin. Application of pharmacokinetics local model to evaluate renal function.Nuclear Science and Techniques, 1999, 10(1): 28

Abstract: The pharmacokinetics local model was used to evaluate renal function. Some typical kinds of renal function cases, normal or disorder, were selected to be imaged with SPECT and those data ıneasured were treated by the pharmacokinetics local model computer program (PLM). The results indicated that parameters, including peak value, peak time, inflexion time, half-excretion time, and kinetic equation played and important role in judging renal function. The fact confirms that local model is very useful in evaluating renal function.

Key words: Renal function, Pharmacokinetics, Local model, SPECT