Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 1998, Vol. 9 ›› Issue (3): 186

Previous Articles     Next Articles

Solution of rate constants in pharmacokinetics local model of nuclear medicine

Cao Guo-Xian, Yu Hui-Xin and Huang Xu-Quan   

  1. State Key Laboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063
PDF ShareIt Export Citation
Cao Guo-Xian, Yu Hui-Xin and Huang Xu-Quan. Solution of rate constants in pharmacokinetics local model of nuclear medicine.Nuclear Science and Techniques, 1998, 9(3): 186

Abstract: Rate constants are important pharmacokinetic parameters and very useful in study of radiopharmaceuticals, nuclide therapy and internal radiation. In the situation of small number of compartments, solution of rate constants is not too difficult. But with increasing compartment number, the calculation is tending to more complex, which makes solving rate constants very difficult. Therefore, according to a general principle a series of formulae is established to simplify the process of solving rate constants.

Key words: Pharmacokinetics, Local model, Rate constants