Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 1991, Vol. 2 ›› Issue (2): 100

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PRELIMINARY STUDY OF TRACE ELEMENTS IN HUMAN BRAIN TUMOUR TISSUES BY INAA

Zhuang Guisun (庄圭苏)1, Wang Yinsong (王茸淞)1, Tan Mingguang (谈明光)1, Zhi Min (支 敏)1, Wang Yongji (王永吉)1, Pan Weiqing (潘伟清)1, Zhang Fulin (张福林)2   

  1. 1 Shanghai Institute of Nuclear Research, Academia Sinica, Shanghai 201800, China;
    Departments of Pathology and Neurology, Huashan Hospital, Shanghai 200040, China
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Zhuang Guisun (庄圭苏), Wang Yinsong (王茸淞), Tan Mingguang (谈明光), Zhi Min (支 敏), Wang Yongji (王永吉), Pan Weiqing (潘伟清), Zhang Fulin (张福林). PRELIMINARY STUDY OF TRACE ELEMENTS IN HUMAN BRAIN TUMOUR TISSUES BY INAA.Nuclear Science and Techniques, 1991, 2(2): 100

Abstract: Elemental profiles of brain tumour tissues from 15 male patients of astrocytomas (grade I- III) and normal human brain tissues of 23 male age matched autopsies as controls have been studied by INAA. A total of 18 elements Se, Na, K, Br, Cl, Mn, Mg. S, Ca, Cu, Hg, Cr, Fe, Rb, Zn, Co, Se and P has been determined for this purpose. The analytical results showed that compared with the normal brain tissues, concentrations of Ca, Fe, Cu, Zn, Mn, Br and Sc were significantly higher in tumour tissues and that of Rb, K and P were lower while no differences for contents of Mg, S, Cr, Na and Cl were observed. A negative correlation between P and Ca in malignant and normal brain tissues was observed.

Key words: Trace element, Brain cancer, NAA