Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2015, Vol. 26 ›› Issue (5): 050304 doi: 10.13538/j.1001-8042/nst.26.050304

• NUCLEAR CHEMISTRY,RADIOCHEMISTRY,RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE • Previous Articles     Next Articles

Radiation effects on physically cross-linked agarose hydrogels

WANG Xiao,1 AO Yin-Yong,1, 2 HUANG Wei,1 LIU Bo,1 AN You,1 ZHAI Mao-Lin 2   

  1. 1Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900, China
    2Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory for Fundamental Science, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
  • Contact: HUANG Wei, ZHAI Mao-Lin E-mail:huangwei839@126.com;mlzhai@pku.edu.cn
  • Supported by:

    Supported by the Science and Technology Development Foundation of China Academy of Engineering Physics (No. 2013B0301035)

PDF ShareIt Export Citation
WANG Xiao, AO Yin-Yong, HUANG Wei, LIU Bo, AN You, ZHAI Mao-Lin . Radiation effects on physically cross-linked agarose hydrogels.Nuclear Science and Techniques, 2015, 26(5): 050304     doi: 10.13538/j.1001-8042/nst.26.050304

Abstract:

As a potential matrix of three-dimensional gel dosimeter, agarose hydrogels will be used for measuring radiation doses, hence the importance of studying their radiation resistance and radiolysis mechanism. Physical property and chemical structure of physically cross-linked agarose hydrogel samples irradiated to 0–200 kGy by 60Co γ-rays were analyzed by universal testing machine, gel permeation chromatography, fourier transform infrared spectrometer, ultraviolet visible spectroscopy, nuclear magnetic resonance, and gas chromatography. The results showed that agarose hydrogels had good radiation stability below 25 kGy, and the maximum compression strength of sample was ca. 0.1MPa at 25 kGy. The irradiated samples degraded obviously and liquefied gradually with increasing doses. Compared with unirradiated sample, carbonyl groups, which generated from the molecular chains of agarose hydrogels, were observed at 25 kGy and increased gradually with dose. The main gas products evolved from irradiated agarose hydrogels were H2, CO2, CO and CH4. Based on the analysis of radiolytic products, the radiolysis mechanism of agarose hydrogels under γ-radiation was proposed.

Key words: Agarose, Hydrogel, γ-radiation, Radiolytic products, Structure analysis