# Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2014, Vol. 25 ›› Issue (3): 030302

### An iterative image reconstruction algorithm for SPECT

ZHAO Jing-Wu,SU Wei-Ning

1. 1Physics School, Nanjing University, Nanjing 210093, China
• Contact: ZHAO Jing-Wu E-mail:jwzhao@nju.edu.cn
• Supported by:

Supported by the Priority Academic Program Development of Jiangsu College Education

ZHAO Jing-Wu, SU Wei-Ning . An iterative image reconstruction algorithm for SPECT.Nuclear Science and Techniques, 2014, 25(3): 030302
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Abstract:

Properties of two algorithms for iterative reconstruction of SPECT images, LS-MLEM and LS-OSEM,are studied and compared with the ML-EM algorithm in this paper. By using projection data of heavy-noise, their effectiveness in improving SPECT image quality is evaluated. A phantom with hot and cold lesion is used in the investigation. The reconstructed images using LS-MLEM or LS-OSEM show that there is not a rapid increase in image noise,and the “best” estimate is assuming that the reconstructed images satisfy the statistical model. The major advantage of using LS-MLEM or LS-OSEM algorithm in SPECT imaging is in their ability to accurately control for heavy-noise. And LS-OSEM algorithm obviously improves the convergence rate.