Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2011, Vol. 22 ›› Issue (3): 165-173 doi: 10.13538/j.1001-8042/nst.22.165-173

• RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICIN • Previous Articles     Next Articles

Monte Carlo simulation for internal radiation dosimetry based on the high resolution Visible Chinese Human

LIU Yang~(1,2)XIE Tianwu~(1,2)LIU Qian~(1,2,*)   

  1. 1 Britton Chance Center for Biomedical Photonics,Wuhan National Laboratory for Optoelectronics,Huazhong University of Science and Technology, Wuhan 430074,China 2 Key Laboratory of Biomedical Photonics of Ministry of Education,College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,China
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LIU Yang, XIE Tianwu, LIU Qian. Monte Carlo simulation for internal radiation dosimetry based on the high resolution Visible Chinese Human.Nuclear Science and Techniques, 2011, 22(3): 165-173     doi: 10.13538/j.1001-8042/nst.22.165-173

Abstract:

The internal radiation dose calculations based on Chinese models is important in nuclear medicine.Most of the existing models are based on the physical and anatomical data of Caucasian,whose anatomical structure and physiological parameters are quite different from the Chinese,may lead significant effect on internal radiation. Therefore,it is necessary to establish the model based on the Chinese ethnic characteristics,and applied to radiation dosimetry calculation.In this study,a voxel model was established based on the high resolution Visible Chinese Human(VCH).The transport procedure of photon and electron was simulated using the MCNPX Monte Carlo code. Absorbed fraction(AF)and specific absorbed fraction(SAF)were calculated and S-factors and mean absorbed doses for organs with ~(99m)Tc located in liver were also obtained.In comparison with those of VIP-Man and MIRD models, discrepancies were found to be correlated with the racial and anatomical differences in organ mass and inter-organ distance.The internal dosimetry data based on other models that were used to apply to Chinese adult population are replaced with Chinese specific data.The obtained results provide a reference for nuclear medicine,such as dose verification after surgery and potential radiation evaluation for radionuclides in preclinical research,etc.

Key words: Internal radiation, AF, SAF, S-factor, Mean absorbed dose