Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2010, Vol. 21 ›› Issue (2): 94-98 doi: 10.13538/j.1001-8042/nst.21.94-98

• RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICIN • Previous Articles     Next Articles

18F-FDG PET/CT for malignant small intestinal neoplasms

SUN Long ZHAO Long LUO Zuoming WEI Jihong SUN Yonghong YANG Rongshui WU Hua*   

  1. Minnan PET Center and Department of Nuclear Medicine, No.1 Hospital Affiliated to Xiamen University, Xiamen 316003. China
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SUN Long, ZHAO Long, LUO Zuoming, WEI Jihong, SUN Yonghong, YANG Rongshui, WU Hua. 18F-FDG PET/CT for malignant small intestinal neoplasms.Nuclear Science and Techniques, 2010, 21(2): 94-98     doi: 10.13538/j.1001-8042/nst.21.94-98

Abstract:

In this paper, 18F-FDG PET/CT data of 19 malignant SINs (small intestinal neoplasms) were consecutively reviewed. Nnine patients accepted PET/CT scan for preoperative diagnosis and staging, while ten patients presented follow-up after treatment and restaging. The results were correlated with abdomen enhanced CT and surgical pathological findings. Abdominal pain and weight loss were the most common findings. About 16% SINs located in the duodenum, 52% in the jejunum and 32% in the ileum. Lymphoma was the most frequent neoplasms. PET/CT revealed residual or recurrent malignant SINs in 5 patients who had negative or non-definite findings by abdomen CT and demonstrated extra-abdomen metastasis in 3 patients. Clinical decisions of treatment were changed for 6 patients after PET/CT examinations. The 18F-FDG PET/CT were better than CT in accuracy, negative predictive value and positive predictive value (89.5% vs 68.4%, 100% vs 66.7%, and 81.8% vs 69.2%, respectively). Whole body 18F-FDG PET/CT may be an effective molecular imaging method for staging and restaging of malignant SINs.

Key words: Malignant small intestinal neoplasm, Staging, Restaging, Molecular imaging, 18F-fluorodeoxyglucose, Positron emission tomography/computed tomography