Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2010, Vol. 21 ›› Issue (2): 80-83 doi: 10.13538/j.1001-8042/nst.21.80-83

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Preparation of silica-coated CdSe QDs for cell imaging applications

XIE Chunjuan1 LI Jian2 YIN Dongguang1,* ZHANG Li1 LIU Binhu1 WU Minghong1,*   

  1. 1 College of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China 2College of Environmental and Chemical Engineering, Nanchang Hangkong University, Nanchang, 330063, China
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XIE Chunjuan, LI Jian, YIN Dongguang, ZHANG Li, LIU Binhu, WU Minghong. Preparation of silica-coated CdSe QDs for cell imaging applications.Nuclear Science and Techniques, 2010, 21(2): 80-83     doi: 10.13538/j.1001-8042/nst.21.80-83

Abstract:

CdSe quantum dots (QDs) were prepared at room temperature by E-beam irradiation of the solution, using ethylene diamine tetraacetic acid as stabilizer. Silica-coated CdSe QDs were made in water-in-oil microemulsion, while amino groups were introduced synchronously onto the nanoparticles by copolymerization of 3-aminopropyl- trimethoxysilane and tetraethyl orthosilicate. The results of TEM imaging, fluorescent spectroscopy and photostability tests show that the QDs are of uniform spherical size (200?8 nm), monodispersity, and high fluorescence and photostability.

Key words: E-beams, Fluorescent quantum dots, Micro-spheres, Reverse microemulsion, Cell labels