Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2009, Vol. 20 ›› Issue (1): 27-30 doi: 10.13538/j.1001-8042/nst.20.27-30

• RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICIN • Previous Articles     Next Articles

Biological reduction and intracellular trapping differences of 188Re(VII) and 99Tcm(VII) in Escherichia coli

XU Fenghua1,2 YIN Duanzhi1,* ZHENG Mingqiang1 WANG Yongxian1   

  1. 1 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China 2 Graduate School of Chinese Academy of Sciences, Beijing 100049, China
PDF ShareIt Export Citation
XU Fenghua, YIN Duanzhi, ZHENG Mingqiang, WANG Yongxian. Biological reduction and intracellular trapping differences of 188Re(VII) and 99Tcm(VII) in Escherichia coli.Nuclear Science and Techniques, 2009, 20(1): 27-30     doi: 10.13538/j.1001-8042/nst.20.27-30

Abstract:

99Tcm is the most commonly used diagnostic radioisotope. And 188Re is an excellent therapeutic radioisotope with a gamma photon for imaging. Both locate in the same group and have very similar properties. 99Tcm(VII) can be partially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli, and trapped intracellularly. However, 188Re(VII) cannot be reduced and trapped,because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons.

Key words: 99Tcm, 188Re, Escherichia coli, Biological reduction, Intracellular trapping