Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2006, Vol. 17 ›› Issue (3): 164 doi: 10.1016/S1001-8042(06)60032-8

• ADVANCED NUCLEAR INSTRUMENTATION AND DETECTION • Previous Articles     Next Articles

High-resolution SPECT for small animal imaging

QI Yu-Jin   

  1. Shanghai Institute of Applied Physics, the Chinese Academy of Sciences, Shanghai 201800, China
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QI Yu-Jin. High-resolution SPECT for small animal imaging.Nuclear Science and Techniques, 2006, 17(3): 164     doi: 10.1016/S1001-8042(06)60032-8
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Abstract: This article presents a brief overview of the development of high-resolution SPECT for small-animal im-aging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pin-hole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection ef-ficiency.

Key words: Small-animal SPECT, Molecular imaging, Pinhole collimation, Gamma camera