Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2020, Vol. 31 ›› Issue (10): 102 doi: 10.1007/s41365-020-00805-7


Methodology development and application of X-ray imaging beamline at SSRF

Hong-Lan Xie1,2 • Biao Deng1,2 • Guo-Hao Du1,2 • Ya-Nan Fu1,2 • Han Guo1,2 • Yan-Ling Xue1,2 • Guan-Yun Peng1,2 • Fen Tao1,2 • Ling Zhang1,2 • Ti-Qiao Xiao1,2   

  1. 1 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    2 Shanghai Synchrotron Radiation Facility (SSRF), Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201204, China
  • Received:2020-06-12 Revised:2020-08-02 Accepted:2020-08-06
  • Contact: Hong-Lan Xie
  • Supported by:
    This work was supported by the National Key Research and Development Program of China (Nos. 2017YFA0403801, 2016YFA0401302, 2017YFA0206004, 2018YFC1200204), and the National Major Scientific Instruments and Equipment Development Project of China (No. 11627901).
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Hong-Lan Xie, Biao Deng, Guo-Hao Du, Ya-Nan Fu, Han Guo, Yan-Ling Xue, Guan-Yun Peng, Fen Tao, Ling Zhang, Ti-Qiao Xiao. Methodology development and application of X-ray imaging beamline at SSRF.Nuclear Science and Techniques, 2020, 31(10): 102     doi: 10.1007/s41365-020-00805-7

Abstract: This paper introduces some latest developments regarding the X-ray imaging methodology and applications of the X-ray imaging and biomedical application beamline (BL13W1) at Shanghai Synchrotron Radiation Facility in the past 5 years. The photon energy range of the beamline is 8–72.5 keV. Several sets of X-ray imaging detectors with different pixel sizes (0.19–24 μm) are used to realize X-ray microcomputed tomography (X-ray micro-CT) and X-ray in-line phase-contrast imaging. To satisfy the requirements of user experiments, new X-ray imaging methods and image processing techniques are developed. In vivo dynamic micro-CT experiments with living insects are performed in 0.5 s (sampling rate of 2 Hz, 2 tomograms/s) with a monochromatic beam from a wiggler source and in 40 ms (sampling rate of 25 Hz, 25 tomograms/s) with a white beam from a bending magnet source. A new X-ray imaging method known as move contrast X-ray imaging is proposed, with which blood flow and moving tissues in raw images can be distinguished according to their moving frequencies in the time domain. Furthermore, X-ray speckle-tracking imaging with twice exposures to eliminate the edge enhancement effect is developed. A high-precision quantification method is realized to measure complex three-dimensional blood vessels obtained via X-ray micro-CT. X-ray imaging methods such as three-dimensional X-ray diffraction microscopy, small-angle X-ray scattering CT, and X-ray fluorescence CT are developed, in which the X-ray micro-CT imaging method is combined with other contrast mechanisms such as diffraction, scattering, and fluorescence contrasts respectively. Moreover, an X-ray nano-CT experiment is performed with a 100 nm spatial resolution. Typical user experimental results from the fields of material science, biomedicine, paleontology, physics, chemistry, and environmental science obtained on the beamline are provided.

Key words: X-ray imaging, X-ray in-line phase-contrast imaging, X-ray micro-CT, Dynamic micro-CT, X-ray speckle-tracking imaging, 3DXRD, SAXS-CT, X-ray fluorescence CT, X-ray nano-CT, Move contrast X-ray imaging