Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2019, Vol. 30 ›› Issue (1): 2 doi: 10.1007/s41365-018-0529-3


Study of neutron production and moderation for Sulfur Neutron Capture Therapy

Meng Peng1,2 • Guo-Zhu He1 • Qi-Wei Zhang1 • Bin Shi1 • Hong-Qing Tang1 • Zu-Ying Zhou1   

  1. 1 Key Laboratory of Nuclear Data, China Institute of Atomic Energy, Beijing 102413, China
    2 College of Liberal Arts and Sciences, National University of Defense Technology, Changsha 410073, China
  • Contact: Peng Meng
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Meng Peng, Guo-Zhu He, Qi-Wei Zhang, Bin Shi, Hong-Qing Tang, Zu-Ying Zhou. Study of neutron production and moderation for Sulfur Neutron Capture Therapy.Nuclear Science and Techniques, 2019, 30(1): 2     doi: 10.1007/s41365-018-0529-3

Abstract: Neutron capture therapy with Sulfur-33, similar to boron neutron capture therapy with Boron-10, is effective in treating some types of tumors including ocular melanoma. The key point in sulfur neutron capture therapy is whether the neutron beam flux and the resonance capture cross section of 33S(n,α)30Si reaction at 13.5 keV can achieve the requirements of radiotherapy. In this research, the authors investigated the production of 13.5 keV neutron production and moderation based on an accelerator neutron source. A lithium glass detector was used to measure the neutron flux produced via near threshold 7Li(p,n)7Be reaction using the time-of-flight method. Furthermore, the moderation effects of different kinds of materials were investigated using Monte Carlo simulation.

Key words: Sulfur Neutron capture therapy, Boron neutron capture therapy, 33S(n,α)30Si resonance reaction, 7Li(p, n)7Be neutron source