Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2018, Vol. 29 ›› Issue (10): 137 doi: 10.1007/s41365-018-0474-1

• NUCLEAR PHYSICS AND INTERDISCIPLINARY RESEARCH •     Next Articles

Investigation of production of medical 82Sr and 68Ge for 82Sr/82Rb and 68Ge/68Ga generators via proton accelerator

Ozan Artun   

  1. Department of Physics, Bu¨lent Ecevit University, 67100 Zonguldak, Turkey
  • Contact: Ozan Artun E-mail:ozanartun@beun.edu.tr
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Ozan Artun. Investigation of production of medical 82Sr and 68Ge for 82Sr/82Rb and 68Ge/68Ga generators via proton accelerator.Nuclear Science and Techniques, 2018, 29(10): 137     doi: 10.1007/s41365-018-0474-1

Abstract:

How to operate 82Sr/82Rb and 68Ge/68Ga generators used in the positron emission tomography scan process is explained, and the importance of 82Sr and 68Ge radionuclides for these generators is revealed. To produce medical 82Sr and 68Ge by means of a proton accelerator in an irradiation time of 24 h, a proton beam current of 250 μA, and an energy range Eproton = 100 → 5 MeV, the cross sections and the neutron emission spectrum curves of (p,xn) reaction processes on Rb-85, Ga-69 and Ga-71 targets were calculated, and the activities and yields of the product were simulated for the reaction processes. Additionally, the integral yields of the reaction processes were determined via the calculated cross-sectional curves and the mass stopping power obtained from the X-PMSP program. Furthermore, based on the obtained results, the appropriate reaction processes for the production of 82Sr and 68Ge isotopes on Rb-85, Ga-69, and Ga-71 targets are discussed.

Key words: Radioisotope production, Proton accelerator, PET, Radioisotope generators