Nuclear Science and Techniques

Abstract:

A facility and method for 109Cd radionuclide-induced energy-dispersive X-ray fluorescent (EDXRF) were developed to determine the Fe, Zn, Br, Rb, and Sr concentrations in the specimens of human prostatic fluid. Specimens of expressed prostatic fluid were obtained from 51 men (mean age 51 years, range 18–82 years) with apparently normal prostates using standard rectal massage procedure. Mean values (M ± SΕΜ) for concentration of trace elements (mg L−1) in human prostate fluid were: Fe 9.04 ± 1.21, Zn 573 ± 35, Br 3.58 ± 0.59, Rb 1.10 ± 0.08, and Sr ≤ 0.76. It was shown that the results of trace element analysis in the micro-samples (20 μL) are sufficiently representative for assessment of the Fe, Zn, Br, and Rb concentration in the prostate fluid. The facility for 109Cd radionuclide-induced EDXRF is comparatively compact and can be located in close proximity to the site of carrying out the massage procedure. The means of Zn and Rb concentration obtained for prostate fluid agree well with median of reported means. For the first time, the Fe and Br concentrations, as well as the upper limit of the Sr concentration, were determined in the human prostate fluid.

Key words: Radionuclide-induced energy-dispersive, X-ray fluorescent analysis, Trace elements, Human prostate, Prostate fluid, 109Cd