Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2016, Vol. 27 ›› Issue (6): 136 doi: 10.1007/s41365-016-0133-3

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Method and portable facility for measurement of trace element concentration in prostate fluid samples using radionuclide-induced energy-dispersive X-ray fluorescent analysis

Vladimir Zaichick1 , Sofia Zaichick2 , German Davydo 1   

  1. 1 Radionuclide Diagnostics Department, Medical Radiological Research Centre, Korolyev St. 4, Obninsk, Russia 249036
    2 Department of Medicine, College of Medicine at Chicago, University of Illinois, COMRB 1160-1168, Chicago, IL 60612, USA
  • Contact: Vladimir Zaichick E-mail:vezai@obninsk.com
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Vladimir Zaichick, Sofia Zaichick, German Davydov. Method and portable facility for measurement of trace element concentration in prostate fluid samples using radionuclide-induced energy-dispersive X-ray fluorescent analysis.Nuclear Science and Techniques, 2016, 27(6): 136     doi: 10.1007/s41365-016-0133-3
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Abstract:

A facility and method for 109Cd radionuclide-induced energy-dispersive X-ray fluorescent (EDXRF) were developed to determine the Fe, Zn, Br, Rb, and Sr concentrations in the specimens of human prostatic fluid. Specimens of expressed prostatic fluid were obtained from 51 men (mean age 51 years, range 18–82 years) with apparently normal prostates using standard rectal massage procedure. Mean values (M ± SΕΜ) for concentration of trace elements (mg L−1) in human prostate fluid were: Fe 9.04 ± 1.21, Zn 573 ± 35, Br 3.58 ± 0.59, Rb 1.10 ± 0.08, and Sr ≤ 0.76. It was shown that the results of trace element analysis in the micro-samples (20 μL) are sufficiently representative for assessment of the Fe, Zn, Br, and Rb concentration in the prostate fluid. The facility for 109Cd radionuclide-induced EDXRF is comparatively compact and can be located in close proximity to the site of carrying out the massage procedure. The means of Zn and Rb concentration obtained for prostate fluid agree well with median of reported means. For the first time, the Fe and Br concentrations, as well as the upper limit of the Sr concentration, were determined in the human prostate fluid.

Key words: Radionuclide-induced energy-dispersive, X-ray fluorescent analysis, Trace elements, Human prostate, Prostate fluid, 109Cd