Nuclear Science and Techniques

《核技术》(英文版) ISSN 1001-8042 CN 31-1559/TL     2019 Impact factor 1.556

Nuclear Science and Techniques ›› 2016, Vol. 27 ›› Issue (1): 22 doi: 10.1007/s41365-016-0022-9

• NUCLEAR CHEMISTRY,RADIOCHEMISTRY,RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE • Previous Articles     Next Articles

Radiation removal of synthetic estrogens in aqueous solution: influence of reduction or oxidation system and toxicity test

Ming-Hong Wu, Jia-Ling Li, Xiang-Xin He, Gang Xu, Guo-Ji Ding, Wen-Yan Shi   

  1. 1. Institute of Applied Radiation, School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China
  • Contact: Wen-Yan Shi E-mail:wyshi1981@shu.edu.cn
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Ming-Hong Wu, Jia-Ling Li, Xiang-Xin He, Gang Xu, Guo-Ji Ding, Wen-Yan Shi. Radiation removal of synthetic estrogens in aqueous solution: influence of reduction or oxidation system and toxicity test.Nuclear Science and Techniques, 2016, 27(1): 22     doi: 10.1007/s41365-016-0022-9

Abstract:

Estrogens as a kind of steroidal sex hormone are widely used in humans, especially quinestrol (QS), dienestrol (DS) and norethindrone (NET, 19-nor-17-alpha-ethinltestoster-one), which cannot be completely degraded after application. Steroidal estrogens at low concentration pulling into environment can disturb the normal biological function of wide life and thus lead to great threat to humans. So it is important to explore its degradation mechanism and its behavior in the environment. In this study, we investigated the oxidation or reduction system under gamma irradiation for reducing estrogenic activity in the aqueous solutions as well as degradation kinetics, its by-products and yield of transformation by different analytical methods such as GC–MS and HPLC. Gamma irradiation could effectively degrade estrogens in aqueous solution. The degradation reaction of estrogens could be depicted by first-order reaction kinetics. The total organic carbon of solution decreased with an increasing absorbed dose with the order: quinestrol > norethindrone > dienestrol. The toxicity of the three estrogens was declined after irradiation. Mono- and quadric-hydroxylated intermediates as well as organic acids were formed after gamma irradiation.

Key words: Dienestrol, Gamma irradiation, Norethindrone, Quinestrol, Synthetic estrogens