Nuclear Techniques ›› 2017, Vol. 40 ›› Issue (2): 20501-020501.doi: 10.11889/j.0253-3219.2017.hjs.40.020501


Autophagy-based mechanistic understanding of healthcare science

LIN Chenglie1,2, LI Jiang1, ZHOU Yi2, SUN Yanhong1, WANG Lihua1, HU Jun1, FAN Chunhai1   

  1. 1. Laboratory of Physical Biology & Bioimaging Center, Shanghai Synchrotron Radiation Facility, Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China;
    2. School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • Received:2016-10-28 Revised:2016-11-14 Online:2017-02-10 Published:2017-01-24
  • Supported by:

    Supported by National Natural Science Foundation of China (No.2013CB932802, No.31371015)


Background: Autophagy is a natural process in cells for self-digestion of intracellular elements, which is highly related to human health. Purpose: To better understand the relationship between autophagy and health issues like cancer, neurodegeneration and aging, we reviewed recent studies on this topic in this paper. We also reviewed some physical stimulations that have effects on health while have been verified capable to induce autophagy, including ionic radiation, physical exercise, acupuncture and massage. Results & Conclusion: We discussed the molecular mechanisms of their effects from the point of autophagy, and looked to the future of healthcare where the regulation of autophagy may be heavily involved.

Key words: Autophagy, Oncology, Neurodegeneration, Radiation, Acupuncture

CLC Number: 

  • Q274