电离辐射激活海马星形胶质细胞诱导小鼠认知功能障碍

doi:10.11889/j.1000-3426.2019.rrj.37.010301

Journal of Radiation Research and Radiation Processing ›› 2019, Vol. 37 ›› Issue (1): 10301-010301.doi: 10.11889/j.1000-3426.2019.rrj.37.010301

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Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice

WANG Zhen¹(),LUO Shishi¹,NIU Lei¹,NAI Aitao²,XU Yang³,LIU Zhenghai¹,HE Jie⁴,HE Shuya⁵,ZHONG Xiaolin⁶,WAN Wei¹(),CAO Wenyu¹()

1. Clinical Anatomy & Reproductive Medicine Application Institute, Medical College, University of South China, Hengyang 421001, China
2. Department of Radiation Oncology, The First Affiliated Hospital of University of South China, Hengyang 421001, China
3. Department of Physiology, Medical College, University of South China, Hengyang 421001, China
4. Department of Pathology, Medical College, University of South China, Hengyang 421001, China
5. Department of Radiation Medicine, School of Public Health, University of South China, Hengyang 421001, China
6. Institute of Clinical Medicine, The First Affiliated Hospital of University of South China, Hengyang 421001, China

Received:2018-09-03 Revised:2018-11-29 Accepted:2018-11-29 Online:2019-02-20 Published:2019-01-30
Contact: Wei WAN,Wenyu CAO E-mail:736887612@qq.com;david-wan@163.com;marksman0@163.com
About author:WANG Zhen (female) was born in July 1990, and graduated from University of South China in 2015. Now she is a master candidate in the Clinical Anatomy and Reproductive Medicine Application Institute of University of South China, E-mail:736887612@qq.com|WAN Wei, associate professor, master’s supervisor, E-mail:david-wan@163.com;Ph.D|CAO Wenyu, Lecturer, E-mail:marksman0@163.com
Supported by:
Supported by the Hunan Provincial Natural Science Foundation of China (2018JJ3460, 2018JJ3429, 2018JJ3464), the Hunan Provincial Natural Science Fund Provincial and Municipal Joint Fund Project (2018JJ4034), the Hunan Provincial Education Department Foundation of China (17B230), Planning Project of Hunan Provincial Health and Family Planning Commission Research Projects (C2016042), the Start-up Funds for Ph.D.s in University of South China (2015XQD27, 2015XQD28), Applied Anatomy and Reproductive Medicine Key Laboratory Construction Project in Hengyang (2017KJ182), and Graduate Student Research Innovation Project of University of South China in 2018 (2018KYY256, 2018KYY258, 2018KYZ065, 2018KYZ069)

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Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice

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