重离子治疗肿瘤中RBE的影响因素及计算方法

doi:10.11889/j.1000-3436.2015.rrj.33.030102

Journal of Radiation Research and Radiation Proces ›› 2015, Vol. 33 ›› Issue (3): 30102-030102.doi: 10.11889/j.1000-3436.2015.rrj.33.030102

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Influencing factors and calculation of RBE in heavy ion radiotherapy

YAN Jiawei ^1,2,3,4 LIU Yang ^1,2,3 ZHAO Qiuyue ^1,2,3,4 ZHANG Hong ^1,2,3

1(Institute of Modern physics, Chinese Academy of Sciences, Lanzhou 730000, China)
2(Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China)
3(Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province, Lanzhou 730000, China)
4(University of Chinese Academy of Sciences, Beijing 100049, China)

Received:2015-03-13 Revised:2015-06-02 Online:2015-06-20 Published:2015-06-12

Abstract

Abstract:

Relative biological effectiveness (RBE), a major factor to determine the absorbed dose, is an important parameter of radiotherapy. Differing from that in the conventional radiation, RBE is a variable value and related with many biological and physical factors in heavy ion therapy. The paper reviews the elements that influence RBE, and briefly introduces the methods to calculate RBE in Japan, German and China.

Key words: Heavy ion radiotherapy, Relative biological effectiveness, Influence factors, Calculation methods

CLC Number:

R730.55，TL99

YAN Jiawei LIU Yang ZHAO Qiuyue ZHANG Hong. Influencing factors and calculation of RBE in heavy ion radiotherapy[J].Journal of Radiation Research and Radiation Proces, 2015, 33(3): 30102-030102.

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Influencing factors and calculation of RBE in heavy ion radiotherapy

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