Journal of Radiation Research and Radiation Processing ›› 2020, Vol. 38 ›› Issue (5): 1-9.doi: 10.11889/j.1000-3436.2020.rrj.38.050101

• REVIEW •    

Research progress on the radioprotective effect of epigallocatechin gallate and its mechanism

XUE Qi,WANG Man,LIU Libo()   

  1. School of Public Health Jilin University, NHC Key Laboratory of Radiobiology, Changchun 130021, China
  • Received:2020-02-19 Revised:2020-05-11 Accepted:2020-05-11 Online:2020-10-20 Published:2020-10-19
  • Contact: LIU Libo E-mail:liulb@jlu.edu.cn
  • About author:XUE Qi (female) was born in February 1995, and obtained her bachelor’s degree from University of North China in 2017. Now she is a graduate student of Jilin University Graduate School of Public Health, focusing on radiology specialty

Abstract:

The radiation protection effect and mechanism of epigallocatechin-3-gallate (EGCG) were reviewed by analyzing and summarizing the literature. EGCG has a radiation protection effect on the hematopoietic system, immune system, and radiation lung injury, and its mechanism of action is related to its scavenging of free radicals, anti-oxidation, anti-apoptosis and other effects.

Key words: Epigallocatechin gallate, Radiation protection, Free radicals, Anti-oxidation, Anti-apoptosis, DNA damage

CLC Number: 

  • R818.74