Journal of Radiation Research and Radiation Proces ›› 2018, Vol. 36 ›› Issue (5): 50101-050101.doi: 10.11889/j.1000-3436.2018.rrj.36.050101

• REVIEW •     Next Articles

A review of the protective effects of genistein against radiation injuries

PANG Zhijun1,2, HE Lei1, ZHOU Jiming1, MA Xiaowen1, ZHANG Xutao1, WANG Zhaowei1, LI Meng1   

  1. 1. Department of Biopharmaceutics, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China;
    2. Clinical Laboratory, 401 General Military Hospital, Qingdao 266000, China
  • Received:2018-06-20 Revised:2018-08-11 Online:2018-10-20 Published:2018-10-29
  • Supported by:

    Supported by National Natural Science Foundation of China (81673020)

Abstract:

In recent years, with the increase of nuclear accidents and the possible need for future war, countries are paying increased attention to the harm caused by radiation injury, and research on drugs that can offer radiation protection is ongoing. Anti-radiation drugs can reduce cell or body damage caused by ionizing radiation and play an important role in radiation protection system. Genistein, a natural active component, has become a hotspot in the research of anti-radiation drugs because of its strong anti-radioactivity and fewer toxic side effects. The research on military radiation injury in the United States has reached the clinical trial stage. In this paper, the recent advances with respect to radioprotective activities of genistein are reviewed.

Key words: Radiation injuries, Genistein, Radiation-protective agents, Review

CLC Number: 

  • Q691