Journal of Radiation Research and Radiation Proces ›› 2017, Vol. 35 ›› Issue (4): 40202-040202.doi: 10.11889/j.1000-3436.2017.rrj.35.040202

• RADIOBIOLOGY AND RADIOMEDICINE • Previous Articles     Next Articles

Feasibility analysis of dose calculation for tumor radiotherapy planning based on cone-beam computed tomography images

MENG Huipeng1,2, FENG Yuanming1, DONG Huajiang1   

  1. 1. School of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin 300072, China;
    2. Radiotherapy Center, Affiliated Hospital of Logistics University of PAP, Tianjin 300162, China
  • Received:2017-05-20 Revised:2017-06-20 Online:2017-08-20 Published:2017-07-29
  • Supported by:

    Supported by Seed fund project of Affiliated Hospital of Logistics University of PAP (No. FYM201620)

Abstract:

Forty cases undergoing RapidArc treatment were selected and grouped equally into head neck group, chest group, abdominal group, and pelvic cavity group. The raw cone-beam computed tomography (CBCT) projections produced in position verification were exported and then scatter-corrected by a self-developed cone-beam CT imaging toolkit (CITK) tool and reconstructed to be 5 mm thick tomographic files, which were then matched with the planning CT to map out the target area by eclipse with all the contour line saved. The radiotherapy of the planning CT and modified CBCT was designed with the same prescription dose, and the optimized conditions, and dose volume histogram (DVH) diagrams were generated and exported through dose calculation by Hounsfield unit-electron density (HU-ED) calibration curves. Finally, the dose distribution index (DDI) values for forty tumor patients were calculated and a t-test was used in the quantitative analysis to discuss whether statistics differences existed between the two methods. Statistical differences between the two methods in the four groups were found in the chest group (t=2.284, p<0.05), while no statistical differences existed (p>0.05) in all the other measurements. The comparative analysis showed that the effectively-corrected CBCT image and the corresponding calibrated HU-ED curves can be used in the dose calculation of tumor radiotherapy planning.

Key words: CBCT (Cone-beam computed tomography), Radiotherapy planning, Dose calculation

CLC Number: 

  • TL72