Journal of Radiation Research and Radiation Proces ›› 2017, Vol. 35 ›› Issue (3): 30101-030101.doi: 10.11889/j.1000-3436.2017.rrj.35.030101

• REVIEW •     Next Articles

A review of the quantitative detection and diagnostic and therapeutic applications of exosomes

SU Jing, SONG Shiping   

  1. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Jiading Campus, Shanghai 201800, China
  • Received:2017-02-28 Revised:2017-03-17 Online:2017-06-20 Published:2017-06-15
  • Supported by:

    Supported by the National Basic Research Program of China (2013CB932800) and the National Science Foundation of China (21373260, 31571014)

Abstract:

This review outlines the biogenesis of exosomes and quantitative methods for exosome detection that have emerged in recent years, including surface plasmon resonance and physical, electrochemical, and microfluidic methods. The applications of exosomes in the diagnosis and treatment of diseases, such as the screening of exosomes as potential tumor markers and the biological effects of radiation-induced exosomes, are summarized. Moreover, future trends in exosome research are forecasted.

Key words: Exosomes, Quantitative determination, Biomarker, Diagnosis and treatment, Radiation, Review

CLC Number: 

  • O653