基于剂量分布指数选择胸部肿瘤最优放疗计划的可行性分析

doi:10.11889/j.1000-3436.2017.rrj.35.010204

Journal of Radiation Research and Radiation Proces ›› 2017, Vol. 35 ›› Issue (1): 10204-010204.doi: 10.11889/j.1000-3436.2017.rrj.35.010204

• RADIOBIOLOGY AND RADIOMEDICINE • Previous Articles Next Articles

Feasibility analysis of selecting optimal radiotherapy plan for chest tumor based on dose distribution index

MENG Huipeng^1,2, FENG Yuanming¹, DONG Huajiang¹

1 School of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin 300072, China;
2 Radiotherapy Center, Affiliated Hospital of Logistics University of PAP, Tianjin 300162, China

Received:2016-09-15 Revised:2016-11-27 Online:2017-02-20 Published:2017-02-20
Supported by:
Supported by Seed Fund Project of Affiliated Hospital of Logistics University of PAP (FYM201620)

Abstract

Abstract:

Dose distribution index (DDI) for fifty chest tumor patients were retrospectively evaluated. The patients were divided into three groups depending on tumor location, including the conventional group, the group with lesion close to the sensitive tissues to be protected, and the chest wall group. For each patient, three tentative plans were designed and recorded during planning, one of which was eventually selected for treatment. When planning target coverage and organs at risk sparing are considered as equally important, the tentative plan with the highest DDI score is shown to coincide with that actually delivered in 35 of the 50 patients considered (70.0%). In 13 of the remaining 15 cases (86.7%), the plan with highest DDI value still coincides with that actually selected, provided that some organs at risk sparing or target coverage is given higher priority than others. DDI provides a non-subjective tool for dosimetric comparison of tentative radiotherapy plans. In particular, DDI readily quantifies differences among competing plans with similar-looking dose-volume histograms and can be easily implemented. It provides a reliable basis to select the best among the tentative radiotherapy plans.

Key words: Dose distribution index (DDI), Chest tumor, Feasibility analysis, Radiotherapy plan

CLC Number:

Q691

MENG Huipeng, FENG Yuanming, DONG Huajiang. Feasibility analysis of selecting optimal radiotherapy plan for chest tumor based on dose distribution index[J].Journal of Radiation Research and Radiation Proces, 2017, 35(1): 10204-010204.

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Feasibility analysis of selecting optimal radiotherapy plan for chest tumor based on dose distribution index

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