Journal of Radiation Research and Radiation Proces ›› 2016, Vol. 34 ›› Issue (5): 50201-050201.doi: 10.11889/j.1000-3436.2016.rrj.34.050201

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Dosimetric comparing four kinds of radiation treatment planning for esophagus cancer

XIONG Qili1,2,3, XU Gang2, SHI Yong4, NI Qianxi3, GU Qiang1   

  1. 1 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Jiading Campus, Shanghai 201800, China;
    2 Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China;
    3 The Affiliated Cancer Hospital of Xiangya School of Central South University, Changsha 410013, China;
    4 The Third Xiangya Hospital of Central South University, Changsha 410013, China
  • Received:2016-06-17 Revised:2016-08-29 Online:2016-10-20 Published:2016-10-14
  • Supported by:

    Supported by the National Natural Science Foundation (No.11175112)

Abstract:

Dose differences among TomoHelical (TH), TomoDirect (TD), Volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) for esophagus cancer were compared. Eighteen esophageal patients were chosen. The Pinnacle 9.2 treatment planning system was used to generate the VMAT plan and the five field IMRT plan. For comparison, the TH plan and five field TD plan were generated by TomoHDTM 2.0.7 treatment planning system. It was available to adopt the dose volume histograms to investigate the dose parameters of target, the statistics of conformity index (CI), the heterogeneity index (HI) of planning target volume (PTV), the dose volumetric parameters of lung, and the spinal cord and heart, total accelerator output monitor units and total treatment time. The results showed that the CI and HI of TH plan was better than TD plan, and VMAT plan was better than IMRT plans, and the first two plans were better than the latter two; the lung's V20Gy and V30Gy, heart's V30Gy and V40Gy of TH plan and VMAT plan were better than those of TD plan and IMRT plan. However, the lung's V5Gy of TD plan had a greater advantage among them. The TH plan was better than TD plan, TD plan was better than VMAT plan, VMAT plan was better than IMRT plan. Taken the cost into consideration, the esophageal VMAT plan is preferred, and considering the therapeutic effect and quality of survival, the TH plan is preferred. When the target volume is relatively large, the low-dose lung is unavailable to achieve the clinical requirements. Therefore it is proposed to use the TD plans to cure the patients. Dose volume histograms are adopted for the statistics of CI, HI of PTV, dose volumetric parameters of lung, spinal cord and heart, total accelerator output monitor units and total treatment time.

Key words: Esophagus cancer, TomoHelical, TomoDirect, Volumetric modulated arc therapy, Intensity modulated radiation therapy, Dosimetric comparison

CLC Number: 

  • TL72