Journal of Radiation Research and Radiation Proces ›› 2016, Vol. 34 ›› Issue (5): 50101-050101.doi: 10.11889/j.1000-3436.2016.rrj.34.050101

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Cellular effects and membrane trafficking of magnetic iron nanoparticles

WANG Lu1,2, XIANG Fawei3, HAN Yuping1,4, WANG Ting1,3, WANG Kun1, WANG Wenfeng1, CHEN Nan1   

  1. 1 Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Zhangjiang Campus, Shanghai 201204, China;
    2 University of Chinese Academy of Sciences, Beijing 100049, China;
    3 Radiology Department, Weifang People's Hospital, Weifang 261000, China;
    4 School of Life Science, Sichuan University, Chengdu 610064, China
  • Received:2016-04-26 Online:2016-10-20 Published:2016-10-14
  • Supported by:

    Supported by National Natural Science Foundation of China (No.U1332119, No.31371015, and No.31470970)

Abstract:

Research progress on biocompatibility, endocytosis and intracellular trafficking, as well as their intrinsic enzymatic activity-related cellular effects of magnetic iron nanoparticles (Fe3O4 NPs) were summarized. These comprehensive researches provide valuable insights for anti-oxidation, autophagy regulation, theranostics, radiation treatment and other biomedical applications of magnetic iron nanoparticles.

Key words: Magnetic iron nanoparticles, Fe3O4 NPs, Enzyme-like activity, Autophagy, Endocytosis

CLC Number: 

  • O611