Journal of Radiation Research and Radiation Proces ›› 2012, Vol. 30 ›› Issue (3): 165-169.doi: 10.11889/j.1000-3436.2012.rrj.30.120307

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Tissue compatibility inspection of central vein catheter sterilized by radiation

LIU Tao1,2  LIU Qingfang1   

  1. 1(School of Radiation Medicine and Public Health, Medical College of Soochow University, Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Suzhou 215123, China)
    2(Wuzhong district CDC, Suzhou 215128, China)
  • Received:2011-11-02 Revised:2012-02-20 Online:2012-06-20 Published:2014-09-11


In order to inspect the security application of radiation sterilization medical products, the cytotoxicity, guinea pigs delayed contact sensitization and skin stimulation tests were carried out to evaluate the tissue compatibility of central vein catheter sterilized by irradiation and the radiation sterilization doses were set according to the ISO11137-2 criterion. The results show that the radiation sterilized samples had no cytotoxicity, no sensitization and no intracutaneous activation that meet the request of tissue compatibility for medical products. It suggests that the central vein catheter sterilized by radiation with set absorbed dose has good tissue compatibility.

Key words: Radiation sterilization, Central vein catheter, Tissue compatibility

CLC Number: 

  • R187